P03-013 - Symptomatic neuromuscular sarcoidosis
نویسندگان
چکیده
Introduction Sarcoidosis is a granulomatous disease possibly affecting all organ systems. Less than 10% of sarcoidosis patients develop symptomatic neurological involvement. Although muscular non-caseating granulomas (NCGs) can be found in up to 75% of sarcoidosis patients, muscular symptoms develop only in less than 0.5% of sarcoidosis patients. Corticosteroids (CS) are the mainstay of medical therapy, but their effect on chronic myopathy is not consistent. Additive immunosuppressive therapy with azathioprine, cyclophosphamide, methotrexate, or chloroquine may be necessary in patients inadequately responding to CSs.
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